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Acyclovir

Acyclovir is used to treat the symptoms of chickenpox, shingles, herpes virus infections of the genitals (sex organs), the skin, the brain, and mucous membranes (lips and mouth), and widespread herpes virus infections in newborns. Acyclovir is also used to prevent recurrent genital herpes infections. Although acyclovir will not cure herpes, it does help relieve the pain and discomfort and helps the sores (if any) heal faster.

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Acyclovir Uses
Acyclovir is also used to prevent recurrent genital herpes infections. Although acyclovir will not cure herpes, it does help relieve the pain and discomfort and helps the sores heal faster.

How to take Acyclovir
Follow the directions for using Acyclovir provided by your doctor. Take Acyclovir with food or milk if it upsets your stomach. Store Acyclovir at room temperature, away from light and moisture. To clean up your infection completely, continue taking Acyclovir for the full course of treatment even if you feel better in a few days. Do not miss any doses. If you miss a dose of Acyclovir, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Acyclovir Side Effects
Side effects, which may go away during treatment, include nausea, vomiting, diarrhea, or headache. If they continue or are bothersome, check with your doctor. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

Acyclovir Precautions
If your symptoms do not improve within a few days or if they become worse, check with your doctor. If you are using Acyclovir for genital herpes, begin using it as soon as you notice symptoms (pain, burning, blisters) of an infection. Use a condom during sexual intercourse. If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Acyclovir during pregnancy. If you are or may be pregnant, check with your doctor for instructions on using Acyclovir during pregnancy. Before you begin taking any new medicine, either prescription or over-the-counter, check with your doctor or pharmacist. Acyclovir is excreted in breast milk. If you are or will be breast-feeding while you are using Acyclovir, check with your doctor or pharmacist to discuss the risks to your baby.

Acyclovir Drug Interactions
Drug interactions can result in unwanted side effects or prevent a medicine from doing its job.

Acyclovir Missed Dose
Try to take each dose at the scheduled time. If you miss a dose, take it as soon as remembered; do not take it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

Acyclovir Storage
Store Acyclovir at room temperature between 59 and 77 degrees F (15 to 25 degrees C) away from heat and light. Keep this and all medications out of the reach of children.

Acyclovir Notes
Acyclovir is most effective if it is started within 48 hours of when the rash first appears.

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DRUG CLASS AND MECHANISM: Viral illnesses differ from bacterial infections in that viruses are not living organisms, but rather take over living cells and reproduce themselves, often at the expense of the host cell. Acyclovir is an antiviral drug which acts against the Herpes viruses, including herpes simplex 1 and 2 (cold sores and genital herpes), varicella-zoster ( and chicken pox), and the Epstein-Barr virus (mononucleosis). Acyclovir inhibits the replication of viral DNA needed to reproduce itself. Virally infected cells absorb more acyclovir than normal cells and convert more of it to an active form which prolongs its antiviral activity where it is most needed.

PRESCRIPTION: yes

GENERIC AVAILABLE: yes

PREPARATIONS: Capsules (200 mg); Tablets (400mg, 800mg); Ointment 5% (15gm).

STORAGE: Acyclovir should be stored at room temperature in a tight container.

PRESCRIBED FOR: Oral acyclovir is used to treat initial genital herpes infections and to treat patients with recurrent (6 episodes per year) severe genital herpes. Acyclovir reduces the pain and the number of lesions in the initial case, and decreases the frequency and severity in those with recurrent infections. In the treatment of shingles, acyclovir reduces pain, shortens the healing time, and limits the spread of virus and the formation of new lesions. Acyclovir can be used to treat chicken pox and acts to reduce healing time, limit the number of lesions, and reduce fever if used within the first 24 hours after the onset of the disease. Acyclovir ointment is used topically to treat initial genital herpes where it has been shown to decrease pain, reduce healing time, and limit the spread of the infection.

DOSING: Acyclovir may be taken with or without food. Acyclovir is excreted mainly by the kidney and dosages need to be reduced in patients with kidney dysfunction.

DRUG INTERACTIONS: Genital herpes is a sexually transmitted disease and patients should avoid intercourse when they have visible lesions. Resistance to acyclovir can develop, especially with overuse. Therefore, acyclovir should be used only for severe cases and only as long as needed. Long-term suppression for recurrent genital herpes should include periodic re-evaluations and trials without the drug or intermittent short-term treatments.

SIDE EFFECTS: Rare side effects in patients treated short-term with acyclovir are nausea, vomiting, and headache. Long-term treatment has the additional potential for rash and.

 



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