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Allegra (fexofenadine HCL)
Allegra is a seasonal allergy medicine that your doctor may prescribe for you if other allergy medicines make you drowsy. Fexofenadine, the active ingredient in Allegra, has been shown not to cause the drowsiness of other antihistamines.
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Important Note
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
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Allegra is an antihistamine. Antihistamines work against the
naturally occurring chemical histamine in your body. |
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Allegra is used to prevent sneezing, runny nose, itching and
watering of the eyes, and other allergic symptoms. |
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Allegra may also be used for purposes other than those listed
in this medication guide. |
How should I take Allegra?
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Take Allegra exactly as directed. If you do not understand these
instructions, ask your pharmacist, nurse, or doctor to explain them to
you. |
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Take each dose with a full glass of water. |
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Allegra is usually taken twice a day, in the morning and the evening.
Follow your doctor's instructions. |
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Do not take Allegra close to a dose of an antacid that contains
aluminum or magnesium such as Rolaids, Maalox, Mylanta, Milk of
Magnesia, Pepcid Complete, and others. These antacids may decrease the
effects of Allegra. |
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Never take more of this medication than is directed by your doctor. If
your symptoms are not being adequately treated, talk to your doctor. |
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Store Allegra at room temperature away from moisture and heat. |
Uses
allegra contains an antihistamine and decongestant used to relieve allergy symptoms such as itchy red eyes, stuffy nose and throat irritation.
How to Use
Take allegra by mouth on an empty stomach 1 hour before or two hours after meals as directed, usually twice daily. Taking this medicine with a high fat meal can decrease its effectiveness. Do not take antacids containing aluminum and magnesium within 2 hours of taking allegra. Swallow the medicine whole. Do not crush or chew the tablet, and do not take more than prescribed. Do not take this product within 14 days after stopping an MAO Inhibitor (see Drug Interactions).
Side Effects
Nausea, stomach upset, trouble sleeping, headache, or cold symptoms may occur. If these persist or worsen, notify your doctor promptly. Unlikely but report promptly: dizziness, mental/mood changes, fast heartbeat, fever. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: fainting, irregular heartbeat. Although drowsiness is very uncommon at usual doses under normal circumstances, be aware that drowsiness may occur and may effect the ability to perfom tasks requiring alertness (e.g., driving). If you notice other effects not listed above, contact your doctor or pharmacist.
Precautions
Tell your doctor your medical history, including: allergies, kidney/urinary problems, enlarged prostate, glaucoma (narrow angle), severe high blood pressure, heart disease, diabetes, thyroid problems (hyperthyroid). Limit alcohol intake, as it may aggravate drug side effects. allegra should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. The pseudoephedrine in this product is excreted into breast milk. Consult your doctor before breast-feeding. Caution is advised when this product is used in the elderly since this group may be more sensitive to side effects.
Drug Interactions
Tell your doctor of all nonprescription and prescription medication you may use, especially: MAO inhibitors (e.g., selegiline, furazolidone, phenelzine, tranylcypromine, moclobemide, procarbazine, linezolid), certain blood pressure drugs (e.g., methyldopa, mecamylamine, reserpine, prazosin), digoxin, all adrenaline-like drugs. Report other drugs which affect the heart rhythm (QTc prolongation), such as: dofetilide, pimozide, quinidine, sotalol, procainamide, sparfloxacin, "water pills" (diuretics such as furosemide or hydrochlorothiazide). Ask your doctor or pharmacist for more details. Check the labels carefully on all nonprescription products, such as cough-and-cold medicines which contain antihistamines and decongestants. Consult your pharmacist. Do not take allegra for several days before any allergy testing since test results can be affected. Do not start or stop any medicine without doctor or pharmacist approval.
Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include irregular or unusually slow or fast heartbeat, unusual nervousness or excitement, rapid breathing, confusion, hallucinations, and seizures.
Notes
Do not share allegra with others.
Missed Dose
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.
Storage
Store at room temperature between 68 and 77 degrees F (20-25 degrees C) away from sunlight and moisture.
Allegra other Information:
Fexofenadine hydrochloride, the active ingredient of ALLEGRA, is
a histamine H1-receptor antagonist with the chemical name (¡À)-4-[1
hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-butyl]-a, a-dimethyl
benzeneacetic acid hydrochloride. It has the following chemical structure:
The molecular weight is 538.13 and the empirical formula is C32H39NO4.HCl.
Fexofenadine hydrochloride is a white to off-white crystalline powder. It is
freely soluble in methanol and ethanol, slightly soluble in chloroform and
water, and insoluble in hexane. Fexofenadine hydrochloride is a racemate and
exists as a zwitterion in aqueous media at physiological pH.
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